In 2025, hackers continue to exploit office files, making them a top attack vector for cybercrime. Understanding these exploits helps you safeguard your organization’s data, devices, networks, and reputation. Here are the top three Microsoft Office-based exploits actively in use and key strategies to defend against them.
Phishing attacks involving Microsoft Office files continue to be prevalent due to their ubiquity and effectiveness. Attackers send fake invoices or reports as Word or Excel files to trick recipients into opening malicious attachments. Many times these emails arrive from someone you know; their email has been compromised (Business Email Compromise). Users who open the attachment are prompted to enable macros or click links. These lead to fake sites that steal credentials or session tokens. Another attack vector sends a QR code as gift certificates. When scanned users visit a malicious website which steals their credentials, session tokens, or initiate malware download.
The above measures focus on exploiting end users through social engineering. They take advantage of the ubiquity of email, attachments, and trusted relationships with known parties. There is another vector of attack here; exploiting missing patches on end user systems. Microsoft released patches for these exploits, but many systems remain unpatched.
Hackers still exploit CVE-2017-11882 in outdated Office versions, despite patches released back in 2017. The Equation Editor flaw lets attackers run code when users open malicious documents without additional clicks. Exploits leveraging this vulnerability often deliver malware like Agent Tesla, an information-stealing Remote Access Trojan (RAT).
.docm
, .xlsm
, .hta
, and .js
at the email gateway or endpoint. Only allow commonly used formats like .docx
or .xlsx
that don’t support embedded macros.Moving on from common attachment exploits, the 3rd actively used exploit in 2025 only requires a single end user click on a malicious file.
The “Follina” vulnerability (CVE-2022-30190) exploits the Microsoft Support Diagnostic Tool (MSDT) via specially crafted Office documents. Attackers embed malicious URLs inside Office documents. When users open them, the URLs trigger remote code execution without macros. This exploit has been used to deploy various payloads, including those concealed through steganography—hiding malicious code within image files.
Run cmd as administrator, and type: reg delete HKEY_CLASSES_ROOTms-msdt /f
Set via Intune, Group Policy, or PowerShell:
Set-MpPreference -AttackSurfaceReductionRules_Ids D4F940AB-401B-4EFC-AADC-AD5F3C50688A -AttackSurfaceReductionRules_Actions Enabled
The enduring exploitation of Microsoft Office vulnerabilities underscores the necessity for continuous proactive security measures. Regularly updating software, educating users, and implementing advanced threat detection mechanisms are essential steps in defending against these persistent threats. By staying informed about current exploit techniques and maintaining robust cybersecurity practices, organizations can mitigate the risks associated with malicious Office documents.
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